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Review Open access Sep 2026

Targeting the gut–bone axis in osteoporosis: probiotic interventions and other microbiota-based therapeutic strategies

ABSTRACT Osteoporosis (OP) is a systemic bone metabolic disorder characterized by impaired bone homeostasis and increased fracture susceptibility. With the rapid aging of the global population, the number of fractures related to osteoporosis continues to increase, along with persistently high rates of disability and mo...

Kun-Yi Zhao, Zhi-Shang Zhang, Zheng Tang et al. · 0 citations
Aug 2026

Pectic oligosaccharides reshape the gut microbiota-mediated intestinal vitamin B7 metabolic network to alleviate metabolic dysfunction-associated steatotic liver disease.

This study identified POS as an effective intervention to alleviate MASLD by restoring intestinal endogenous VB7 supply, providing a strong rationale for developing POS as a therapeutic prebiotic.

Zizhen Yang, Yujia Fu, Shuhan Liu et al. · 0 citations

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