ACOT7 promotes HNSCC progression by disrupting the AKT-MDM2-p53 axis
Head and neck squamous cell carcinoma ( HNSCC ) is a prevalent malignancy with poor clinical prognosis. While acyl-CoA thioesterases ( ACOTs ) are recognized as key regulators of lipid metabolism, their contributions to HNSCC pathogenesis are not well understood. ACOT7 is of particular interest as it cataly...