Open access
Aug 2026
Blood-brain barrier-penetrant nanotherapy inhibits haem oxygenase-1-mediated ferroptosis for post-resuscitation neuroprotection
Zwitterionic poly (tertiary amine oxide)-based micelles that cross the BBB via transcytosis and deliver artesunate to suppress haem oxygenase-1-driven ferroptosis, restore iron homeostasis and provide neuroprotection after resuscitation are reported.
Mao Zhang, Wen-Bin Zhang, Qiu-Yu Wei et al.
· Nature Communications · 0 citations