Author

Jiacheng Qiu

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Open access Jul 2026

NRGN inhibits CD8⁺ T cell effector function by downregulating MHC-I expression through the FMR1-IRF8 axis in hepatocellular carcinoma.

Modulation of the NRGN-IRF8-MHC-I axis could represent a potential strategy for improving immunotherapeutic responses and sustain suppression of antigen presentation in HCC.

Dong-Jie Ye, Jiacheng Qiu, Hao-Yi Yang et al. · Journal of experimental & cl... · 0 citations