Jul 2026
Shared Genetic Architecture of Epilepsy and Glioma Revealed by Mendelian Randomization: Identifying Prognostic Biomarkers and Therapeutic Targets.
These findings support a neuroimmune model in which pleiotropic germline variants act via microglia and excitatory neurons to link seizure biology with tumor immunity and prognosis, and reveal a common genetic architecture between glioma and epilepsy.
Xiangling Feng, Jiahao Zhou, Zhen He et al.
· Current Cancer Drug Targets · 0 citations