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Author

Jiaheng Lou

2 papers indexed here

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Open access Sep 2026

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

ABSTRACT Chronic stress frequently occurs in patients with cancer, yet how stress is translated into pro‐metastatic programs remains unclear. Here, using chronic restraint stress (CRS) in male mice, we show that stress increases metastatic burden and reduces survival in lung metastasis and peritoneal dissemination mode...

Si-Cheng Zhao, Zhi-Yuan Song, Jing-Cheng Zhang et al. · 0 citations
Open access Sep 2026

Candidate Spatial Niches Associated with Gastric Cancer Metastasis and Treatment Resistance: Functional Classification, Evidence Boundaries, and a Translational Framework

Gastric cancer metastasis and poor treatment responses are spatially heterogeneous; however, single-marker positivity, cellular enrichment, or simple colocalization alone is insufficient to establish a functionally meaningful spatial niche. Within this framework, “treatment resistance” encompasses primary nonresponse,...

Yi Huang, Jing-Cheng Zhang, Jiaheng Lou et al. · 0 citations

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