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Jialu Hu

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Open access Aug 2026

SpatialMOC: Accurate reconstruction of spatial multi-omics landscapes through cross-modality prediction

Across multiple tissues, molecular modalities, developmental stages, sequencing platforms, and degraded datasets, SpatialMOC consistently outper-formed existing computational approaches in bidirectional molecular prediction and establishes SpatialMOC as a general framework for spatial multi-omics reconstruction.

Zhengxuan Liu, Peimeng Zhen, Bingtao Wang et al. · 0 citations
Jul 2026

Mosaic integration of spatial multiomic data based on hierarchical graph contrastive learning with SpatialMOSI.

SpatialMOSI provides a critical computational foundation for constructing integrative 3D molecular atlases from complex multimodal spatial data sets and demonstrates SpatialMOSI's versatility across multiple biological systems, accurately identifying spatially conserved domains, imputing missing omic layers, and recons...

Peimeng Zhen, Han Shu, Bingtao Wang et al. · 0 citations
Aug 2026

Predicting circRNA-Drug Sensitivity Using Integrated Hybrid Graph and Molecular Features.

Case studies further validated predicted circRNA-drug associations, including cisplatin, enzalutamide, and sorafenib, against published experimental findings, demonstrating HMCDSP's capacity to reveal clinically relevant biomarkers and inform personalized therapeutic strategies.

Yong-Tian Wang, Wen-Kai Shen, Jiahao Li et al. · 0 citations

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