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Open access Aug 2026

Analysis of Differential Gene Expression and Alternative Splicing in Ovaries of High- and Low-Prolificacy Sheep Using Nanopore Full-Length Transcriptome Sequencing

Reproductive efficiency determines the economic benefits of the sheep industry, yet the molecular mechanisms underlying prolificacy remain incompletely understood. To investigate transcriptomic differences associated with sheep prolificacy, we performed Oxford Nanopore Technologies (ONT) full-length transcriptome seque...

Jian-Zhi Fu, Zhibin Ji, Dejie Zhu et al. · 0 citations
Open access Jul 2026

Integrative ATAC-seq and RNA-seq analysis reveals lactation performance between Sewa sheep and east Friesian sheep.

This study integrated ATAC-seq and RNA-seq to compare chromatin accessibility landscapes and transcriptomic in mammary gland tissues from Sewa sheep and East Friesian sheep, providing new insights into the epigenetic regulatory mechanisms underlying lactation performance differences in sheep.

Wentao Li, Jiamin Xu, Jiashun Sheng et al. · 0 citations

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