Jul 2026
Targeting KIF11 degradation: Oxypeucedanin inhibits lung adenocarcinoma progression by disrupting the MCM2-CDK1 signaling pathway.
OPD functions as a novel molecular degrader of KIF11, exerting its anti-LUAD effects by promoting KIF11 ubiquitination and subsequent proteasomal degradation.
Wenting Wu, Yinhua Gong, Liying Zhang et al.
· Phytomedicine · 0 citations