A Janus-type polycaprolactone/chitosan scaffold with dual functions of leakage prevention and osteogenesis for skull base defect repair.
To address the critical scientific challenge of achieving synergistic repair of cerebrospinal fluid leakage prevention and bone regeneration in skull base defects, an innovative Janus-type bilayer scaffold with dual functions of "leakage prevention and osteogenesis" was designed and fabricated by electrospun and freeze...