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Open access Sep 2026

Circulating Serum AGRN and ADAMTS8 With Related Candidates as Potential Biomarkers for Carotid Plaque Presence and Vulnerability

ABSTRACT Background Carotid atherosclerosis is a major etiologic substrate for ischemic stroke. Although imaging can characterize stenosis and plaque morphology, circulating biomarkers may better support screening and scalable risk stratification, yet reliable serum protein markers for carotid plaque, particularly for...

Shuai-Wei Guo, Sheng-Yan Cui, Xiao Zhang et al. · 0 citations
Open access Sep 2026

EXPRESS: Diagnostic Accuracy of Noninvasive Translesional Pressure Ratio Based on Magnetic Resonance Imaging for Intracranial Atherosclerotic Stenosis: A Validation Study.

The anatomic stenosis severity of intracranial atherosclerotic stenosis (ICAS) does not reliably reflect lesion-specific hemodynamic impairment, and invasive pressure-wire assessment is technically challenging in the cerebral circulation. This study aimed to develop and validate MRI-derived pressure ratio (M-PR), a non...

Yi-Fan Yang, Ji-Chang Luo, Long Li et al. · 0 citations

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