Open access
Aug 2026
CD300f negatively regulates microglial pyroptosis via the JAK2/STAT3 axis in sepsis-associated encephalopathy.
It is demonstrated that CD300f negatively regulates JAK2/STAT3 phosphorylation, attenuates microglial pyroptosis, and alleviates cognitive dysfunction in SAE mice, highlighting an association between CD300f and neuroprotection in SAE and suggest its potential as a therapeutic target, warranting further investigation th...
Xue Chen, Ye Sun, Sai-Nan Jiang et al.
· International Immunopharmaco... · 0 citations