Open access
Jul 2026
Antibody-mediated CAR T Platform for Targeting Tumor Cells and the Tumor Microenvironment 2301697
A dual-targeting strategy disrupted the TME-induced immune suppression, reduced collagen deposition, and boosted T cell activity, resulting in notable tumor growth inhibition and prolonged survival in both subcutaneous and orthotopic pancreatic cancer models.
Yiming Zhou, Jian-Chuan Wang, Yufei Du
· Journal of Immunology · 0 citations