Author

Jian Dong

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Sep 2026

Nanocatalytic Phase Separation Augments Tumor‐specific cGAS‐STING Activation for Spinal Metastasized Breast Cancer Metalloimmunotherapy

The cGAS‐STING pathway is a pivotal therapeutic target for antitumor immunity, yet clinical translation of its small‐molecule agonists is hindered by poor tumor specificity, suboptimal pharmacokinetics, and systemic off‐target effects. Here, we report a nanocatalytic strategy based on a tumor microenvironment (TME)‐res...

Hao Qin, Jia-Qian Wang, Jian Zhou et al. · Advanced Healthcare Material... · 0 citations

Open access Jul 2026

Highly penetrative nanocarrier modulates tumor bacteria to enhance oxygen-free photo immunotherapy in spinal metastatic cancer.

A novel charge-enrichment and light-activated biomimetic nanosystem, designated as polyion liquid-bridged eosin Y (PIL-BEY), which offers a promising strategy for treating invasive metastatic tumors.

Chao Jia, Hongwei Lu, Jin-Jin Wang et al. · Journal of Nanobiotechnology · 0 citations