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Jian-Feng Xu

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Aug 2026

Deubiquitination of ME1 by OTUD7B promotes aerobic glycolysis of esophageal cancer.

Esophageal cancer (EC) is among the most prevalent malignancies worldwide. Malic enzyme 1 (ME1), which catalyzes the oxidative decarboxylation of malate to pyruvate, contributes to the Warburg effect (aerobic glycolysis) and plays a pivotal role in the progression of tumor growth. Nevertheless, the functional contribut...

Liyang Guan, Xin Li, Zaixing Du et al. · 0 citations

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