AI-guided network analysis of TCGA-PAAD prioritizes biologically coherent KRAS-axis and stromal-inflammatory candidates with clinically available HER2, EGFR, MEK-, BRAF, and KRAS-pathway inhibitors, supporting hypothesis generation for future pancreatic cancer interception studies.
Jian-Fu Li, Yingyun Yang, Michael B. Wallace et al.· Clinical Cancer Research· 0 citations
By tracing the evolutionary trajectories of these methodologies, this scoping review provides a mechanism-centered framework to inform responsible model development and deployment in medical settings, tailored to task complexity, data characteristics, and resource constraints.
Fang Li, Jian-Fu Li, Weiguo Cao et al.· npj Health Systems· 0 citations
The high occult prevalence motivates germline-guided active surveillance for genetically at-risk young adults rather than symptom-driven workup, anchoring next-generation surveillance trial designs in rare and hereditary pancreatic malignancies.
Jian-Fu Li, Yingyun Yang, Wallace Michael et al.· Cancer Research· 0 citations
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