Open access
Oct 2026
Long-Term Treadmill Exercise Improves Spatial Memory and Increases SOX2-Positive Cells in the Hippocampus of Middle-Aged Male Mice.
Age-related cognitive decline is closely associated with hippocampal deterioration, yet the cellular and molecular adaptations underlying exercise-induced cognitive improvement remain incompletely understood. In the present study, nine-month-old male C57BL/6J mice were randomly assigned to a treadmill exercise group or...
Rong-Song Yi, Qi Zhao, Wei-Min Zhang et al.
· Brain Research Bulletin · 0 citations