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Author

Jian Huang

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Review Open access Aug 2026

Multiomics Insights Into AL Amyloidosis

Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates. Recent adv...

Zi-Xuan Zhang, Ziru Huang, Hao-Xian Tang et al. · 0 citations
Jul 2026

Transcriptomic Profiling Identifies MyD88 and Pik3r3 as Hub Genes Associated with the Anti-hypertrophic Effects of B-type Natriuretic Peptide.

INTRODUCTION B-type natriuretic peptide (BNP) is widely used to diagnose and assess heart failure prognosis. However, its effects on pathological cardiomyocyte hypertrophy and the underlying mechanisms remain largely unexplored. METHODS Here, we report the use of isoproterenol (ISO)-induced cardiomyocyte hypertrophy...

Changchun Wu, Yaqing Wang, Zixuan Zhang et al. · 0 citations

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