Claudin 1 promotes blood-borne metastasis by modulating the Src/Ezrin signaling pathway in high-CLDN1 triple-negative breast cancer model
ABSTRACT This study aimed to elucidate the role and mechanism of CLDN1 in regulating migration and metastasis in triple‑negative breast cancer (TNBC). In vivo, an orthotopic TNBC model was used to evaluate circulating tumor cells and lung metastasis; in vitro, cell migration, F‑actin organization, and protein expressio...