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Jian-Lei Cao

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Open access Aug 2026

PLCE1 exacerbates the development of atherosclerosis by driving endothelial dysfunction and macrophage inflammation via targeting CTNNB1

The infiltration of macrophages and the inflammatory response they mediate, which are initiated by endothelial dysfunction, are pivotal in both the initiation and progression of atherogenesis. Phospholipase C epsilon 1 (PLCE1) is significantly involved in cardiovascular diseases, in part due to its regulation of va...

Wen-Lin Cheng, Yu-Fang Shi, Quan Zhang et al. · 0 citations

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