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Jian Li

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Open access Oct 2026

Three ABO 3′ splice-site variants including a novel one converge on a common splicing defect to attenuate blood group antigen expression

Background ABO subtypes are characterized by attenuated antigen expression, rendering them susceptible to serological misclassification and posing substantial risks to transfusion safety. Splice-site variants represent one of the mechanisms underlying ABO subtype formation; however, previous mechanistic investigations...

Hong-Li Guan, Ya-Lan Yang, Jian Li et al. · 0 citations

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