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Open access Aug 2026

DUSP1 Inhibits Mechanotransduction and MAPK Signalling to Alleviate Myocardial Cell Hypertrophy.

Hypertrophic Cardiomyopathy (HCM) is one of the significant causes of heart failure. This study aimed to identify and validate potential therapeutic targets for HCM through bioinformatics analysis and in vitro and in vivo experiments. By analysing differentially expressed genes in HCM patients and combining multiple an...

Xiaoyuqian Zhong, Ling-Ran Kong, You-Jun Zhang et al. · 0 citations
Open access Aug 2026

Transcriptome expression profiles and regulatory networks in patients with heart failure following myocardial infarction

The molecular mechanisms underlying heart failure (HF) following myocardial infarction (MI) (HF-MI) remain incompletely understood, and discoveries from whole-transcriptome profiling hold significant promise for disease prevention and treatment. Whole-transcriptome sequencing was performed on whole blood f...

Yangyang Yuan, R. Long, Zewen Wei et al. · 0 citations

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