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Open access Sep 2026

Biphasic, Time-Dependent Roles of NK1.1⁺ Cells In Retinal Injury and Repair

To investigate the stage-specific role of NK1.1⁺ cells in two experimental models of retinal injury: laser-induced choroidal neovascularization (CNV) and retinal detachment (RD). The study used C57BL/6J mice (8–12 weeks). NK1.1 + cells were depleted either during the acute phase (< 48 h after injury) or throughou...

Xue-Xue Cui, Rui-Qi Zhou, Cai-Jiao Yi et al. · 0 citations
Open access Aug 2026

The Integrin-Mediated Focal Adhesion Is Critically Involved in the Macrophage-to-Myofibroblast Transition in Subretinal Fibrosis.

Fibrosis, a common endpoint of chronic inflammatory diseases across organs, remains a major therapeutic challenge. Macrophages are central regulators of fibrotic remodeling, with evidence suggesting their direct role through macrophage-to-myofibroblast transition (MMT). However, the upstream mechanisms governing macrop...

Wen Deng, Cai-Jiao Yi, Jian Liu et al. · 0 citations

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