Author

Jian Ma

2 papers indexed here

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Open access Oct 2026

Structural variants from donor-specific assemblies affect recurrent chromatin contact divergence in humans

GRAPHICAL ABSTRACT Structural variants (SVs) are a major source of human genetic diversity, yet their contribution to three-dimensional (3D) genome organization remains difficult to resolve using a standard reference genome. Here, we integrate haplotype-resolved chromatin interaction maps across 354 human and 12 nonhum...

L. Ni, Jia-Dong Lin, DongAhn Yoo et al. · bioRxiv · 0 citations

Open access Sep 2026

A meta-interaction basis for cell-cell communication in tissues

Tissue function depends on signals exchanged between cells and the responses they elicit. Yet whether diverse cell-cell interactions in situ form recurrent sender-receiver programs remains un-clear. We present SpiderNet, an interpretable representation-learning framework that discovers such directed programs as a compa...

Jun-Jie Tang, Shao-Heng Liang, Shahul Alam et al. · bioRxiv · 0 citations