Jian-Ping Xie

Accumulation of Polyphosphate Inhibits Biofilm Formation in Mycobacteria by Activating RegX3 to Reduce Intracellular c-di-GMP Levels

Mycobacterium tuberculosis can persist in the host for prolonged periods. Biofilm formation represents a key strategy that promotes bacterial persistence, enhances antibiotic resistance, and facilitates immune evasion. Thus, targeting biofilm formation holds significant therapeutic potential for tuberculosis. Exopoly...