Asymmetric Hydroformylation of Aryl Vinyl Ethers to Chiral 2-Aryloxypropanals: Access to Aryloxypropionic Acid Herbicide Precursors.
Enantiopure aryloxypropionic acid herbicides are of considerable importance in modern crop protection, creating a strong demand for efficient catalytic approaches to their synthesis. Herein, we report a Rh/(S,R)-DTB-YanPhos-catalyzed asymmetric hydroformylation of readily available aryl vinyl ethers, affording chiral 2...