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Jian-Sen Yu

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Sep 2026

Nobiletin Attenuates Doxorubicin-Induced Cardiotoxicity by Promoting Pyruvate Kinase M2 Tetramerization.

BACKGROUND Doxorubicin (DOX) is an effective chemotherapeutic agent whose clinical use is limited by dose-dependent cardiotoxicity. Although nobiletin (NOB) exhibits cardioprotective effects in cardiovascular diseases, its role and underlying mechanisms in doxorubicin-induced cardiotoxicity (DIC) remain unclear. METH...

Xin-Qing Dai, Ming-Yue Tang, Ya Wu et al. · 0 citations

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