Review
Open access
Nov 2026
Neuro-immune-tumor microenvironment interactions in pancreatic cancer: mechanisms and targeted therapeutic strategies
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), is highly aggressive and resistant to conventional treatment. Perineural invasion (PNI) and bidirectional neuroimmune signaling contribute to tumor progression, immune evasion, pain, and treatment resistance. This review integrates the morpholog...
Fu-Qiang Tian, Yan Cai, Yue-Hong Li et al.
· Journal of Translational Med... · 0 citations