Jian-Wei Yang

PRDX1 facilitates USP7-dependent stabilization of SCD1 and promotes bladder cancer progression.

Bladder cancer is characterized by redox adaptation and metabolic plasticity, but the mechanisms linking these processes remain incompletely understood. Integrating bulk, single-cell, and spatial transcriptomic analyses, we identified PRDX1 as a malignant epithelial cell-associated factor linked to adverse outcome. Gen...

Artificial intelligence and surgical data science in robot-assisted radical prostatectomy: global research trends, knowledge structure, and emerging frontiers

Single-cell and spatial transcriptomics identify CAPG as a key driver of cisplatin resistance in bladder cancer

This study links resistance-associated cellular states to a functionally validated regulator and provides an integrative framework for identifying clinically relevant regulators of chemotherapy resistance in bladder cancer.

Guideline-based evaluation of large language models for patient counselling before robot-assisted radical prostatectomy: accuracy, safety, and readability