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Review Open access Sep 2026

Targeting the GABA receptor for agricultural Pest control: from molecular mechanisms to novel NAM site inhibitors.

The ionotropic γ-aminobutyric acid receptor (GABAR) is a major inhibitory neurotransmitter receptor in the insect central nervous system and a proven target for multiple classes of insecticides. The recent discovery of the NAM binding site located at the transmembrane subunit interface has revitalized interest in this...

Zhao-Kai Yang, Yongfu Guo, Han Yan et al. · 0 citations
Open access Sep 2026

Novel cationic pyridine-phenylamide compounds: design, synthesis, and mechanism of action as antibacterial agents.

BACKGROUND Plant bacterial diseases caused by Xanthomonas oryzae pv. oryzicola (Xoc) and Xanthomonas axonopodis pv. citri (Xac) cause severe yield losses, and increasing resistance to existing bactericides demands novel antibacterial agents. Guided by a molecular hybridization and cationization strategy, a series of py...

Ya-Ming Liu, Jia-Xin Wang, An-Jing Liao et al. · 0 citations

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