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Jian-Xin Chen

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Open access Oct 2026

Modified BRICS sequential regimen in advanced hepatocellular carcinoma patients with BCLC C stage: a real-world study

Patients with advanced hepatocellular carcinoma (HCC) have limited treatment options and poor prognosis. This study evaluates the efficacy and safety of a modified BRICS (Bifidobacterium-based probiotics, Radiotherapy, Immunotherapy, and anti-angiogenic therapy with a Stereotactic approach) sequential regimen in a real...

Jian Wang, Jun-Hui Wang, Yong-Hai Peng et al. · 0 citations
Open access Oct 2026

Comparative Efficacy of First-Line versus Further-Line Icotinib Therapy in Advanced Lung Adenocarcinoma: A Real-World Cohort Study

Background The optimal sequencing of EGFR tyrosine kinase inhibitors (TKIs) in advanced lung adenocarcinoma remains controversial. This study aimed to compare the efficacy of icotinib as first-line versus further-line therapy in a real-world setting. Methods A retrospective cohort study was conducted at Quzhou People’s...

Xue-Li Zhang, Jun-Hui Wang, Jian-Xin Chen · 0 citations

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