Author

Jian Zhang

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Open access Aug 2026

Knowledge-driven multimodal mutual learning for cell line-targeted anticancer peptide prediction.

A hybrid dataset compiled from five well-established peptide databases is integrated and proposed, and the effectiveness of TargetPC is demonstrated, which outperforms the state-of-the-art baselines in terms of prediction accuracy, and maintains strong generalization to unseen ACPs and cell lines.

Xuan Liu, Jian Zhang, Chong-Yang Chen et al. · Bioinformatics · 0 citations

Open access Aug 2026

DNAreader: accurate prediction of DNA-binding residues in structured and disordered proteins using transformers and contrastive learning

This work introduces DNAreader, the first predictor specifically designed to predict DBRs in the structured and disordered sequence regions, and develops the DNAreaderDBIDR module, which accurately predicts DNA-binding IDRs, providing flexibility to identify DBRs within IDRs or to predict entire disordered DNA-binding...

Jian Zhang, Sushmita Basu, Jingjing Qian et al. · Nucleic Acids Research · 0 citations