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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Jian Zhang

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Open access Aug 2026

A knowledge-driven framework for predicting single-cell responses for unprofiled drugs

Predicting cellular response to chemical perturbations is critical to build virtual cells, yet experimentally profiled compounds cover only a small fraction of this space. Existing models struggle to generalize to unprofiled compounds, as they typically treat drugs as isolated identifiers without encoding their mechani...

Jinghao Feng, Zi-Heng Zhao, Xiaoman Zhang et al. · 1 citation
Open access Aug 2026

Discovery of Aurora A/HDAC dual-target inhibitors: broad-spectrum in vitro antitumor activity and in vivo pharmacokinetic limitations.

Z20 is a potent Aurora A/HDAC dual-target inhibitor in vitro, while its pharmacokinetic defects limit clinical potential, which highlights the necessity of optimizing pharmacokinetic profiles for translating in vitro potency to in vivo efficacy.

Li-Rong Zhang, Xuewen Zhang, Jie Zhong et al. · 0 citations

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