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Author

Jian Zhang

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Open access Jul 2026

RNA exonuclease REXO4 resolves m6A-marked R-loops and suppresses anti-tumor immunity.

Transcription blockage frequently occurs in tumor cells, and aberrant R-loop formation during this process drives genome instability. However, the regulation of R-loop homeostasis and its contribution to tumorigenesis remain to be investigated. Here, we report that the RNA exonuclease REXO4 resolves R-loops by 3'-5' ex...

Jieyou Zhang, Kaiwen Bao, Yayan Hou et al. · 0 citations

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