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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Jianbo Wu

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2 papers indexed here

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Aug 2026

MiR-485-5p targets RGS4 to promote angiogenesis in lower limb ischemia by activating VEGFR-2/AKT/ERK1/2 signaling.

Angiogenesis is critical for post-ischemic tissue repair. Although miR-485-5p is highly expressed in vascular tissues and RGS4 regulates angiogenesis, their specific roles under hypoxia remain largely unknown. This study aimed to elucidate these functions and underlying mechanisms. Using a CoCl₂-induced hypoxic model i...

Mengting Li, Yulin Luo, Yufei Li et al. · 0 citations
Open access Jul 2026

Brazilin attenuates methylglyoxal-induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR-mediated autophagy/apoptosis axis in vitro and in vivo

Methylglyoxal (MGO), a glycolytic metabolic byproduct and major precursor of advanced glycation end products (AGEs), accumulates and is critically involved in diabetes, particularly in diabetic vascular complications. In endothelial cells (ECs), MGO has been implicated in oxidative stress and inflammatory responses, an...

Yu Liang, Jinxiang Chen, Haiyang Li et al. · 0 citations

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