Open access
Jul 2026
Insulin gene-modified 3D stem cells for enhanced islet regeneration and systemic reversal of type 1 diabetes
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the destruction of pancreatic β cells, leading to lifelong insulin dependence and an increased risk of severe complications. Three-dimensional stem cells (3D SCs) culture systems have emerged as a superior alternative by more accurately mim...
Qian Li, Xiao Ma, Kefei Yuan et al.
· Stem Cells Translational Med... · 0 citations