Dysregulation of Calcium Signaling Homeostasis in the Onset and Progression of Alzheimer's Disease and Its Therapeutic Potential
Alzheimer's disease (AD), the most common neurodegenerative disorder, accounts for 60–70% of all dementia cases and is clinically characterized by progressive memory impairment, executive dysfunction, and neuropsychiatric symptoms. The traditional pathogenic framework has focused on β-amyloid (Aβ) deposition and Tau ne...