Jiang-Lin Wang

SOX4 drives ferroptosis resistance of non-small cell lung cancer by regulating PI3K/AKT/SREBP1/SCD1 signaling axis

Non-small cell lung cancer (NSCLC) remains a challenging disease due to its high heterogeneity and the lack of effective treatment strategies. Ferroptosis, a recently identified form of regulated cell death driven by the accumulation of lipid hydroperoxides, has emerged as a promising therapeutic strategy in NSCLC. W...