Review
Open access
Sep 2026
Loss of Heterozygosity in Chromosome 11q13 Covering MEN1 and AIP Associates with Aggressive Features in Pituitary Tumors
Around 10% of pituitary tumors are estimated to be aggressive and associated with poor prognosis. Loss of heterozygosity (LOH) in chromosome 11q13 has been observed in aggressive pituitary tumors (APTs). Both MEN1 and AIP, located on 11q13 with an interval of 2.7 Mb, have been discovered as genetic markers of APTs. We...
Shi Chen, Jia-Qi Qiang, Lin Lu et al.
· Health and Metabolism · 0 citations