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Author

Jiang Zheng

2 papers indexed here

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Aug 2026

Cantharidin Causes Hepatotoxicity by Disrupting GSH-Mediated Redox Homeostasis.

Cantharidin (CTD) possesses potent anticancer activity, whereas its prominent hepatotoxicity severely limits its clinical application. Because the detailed molecular mechanisms responsible for CTD-triggered hepatotoxicity have not been fully elucidated, additional investigations are necessary to uncover its toxicologic...

Hong Tang, Qing Rao, Ting Liu et al. · 0 citations
Aug 2026

CYP2C19-Mediated Metabolic Activation and OAT3/P-gp-Associated Transport Contribute to Dioscorea bulbifera L.-Induced Hepatotoxicity.

ETHNOPHARMACOLOGICAL RELEVANCE Dioscorea bulbifera L. (DBL) is a traditional medicinal herb, but its clinical use is often limited by its potential to cause herb-induced liver injury. 8-Epidiosbulbin E acetate (EEA) is recognized as the major hepatotoxic constituent in DBL; however, the mechanisms underlying the drug t...

Yu-Wei Tian, Liping Deng, Weiyu Guo et al. · 0 citations

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