Open access
Aug 2026
Differential circadian time modulates of dentate gyrus and CA1 excitation-inhibition balance and seizure threshold
Circadian rhythms regulate seizure threshold and neuronal excitability in epilepsy. Temporal lobe seizures tend to arise more frequently during the diurnal phase relative to the nocturnal phase, yet dentate gyrus (DG) granule cells display elevated intrinsic excitability and CA1 pyramidal neurons show enhanced synapt...
Rong-Jing Ge, Mengru Zhang, Dao-Ming Cheng et al.
· Molecular Brain · 0 citations