Open access
Jul 2026
Association of TPH2 polymorphisms with valproic acid efficacy and neurological adverse events in pediatric epilepsy
TPH2 rs4570625 may serve as a potential exploratory biomarker for predicting VPA efficacy and neurological toxicity in pediatric epilepsy, mediated through serotonergic pathway dysregulation.
Jiahao Zhu, Xixuan Wang, Xianhuan Shen et al.
· Frontiers in Pharmacology · 0 citations