Author

Jianwei Wang

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Open access Aug 2026

The EV-A71 RNA-binding protein Matrin 3 facilitates viral replication by stabilizing viral RNA via ZDHHC20-mediated palmitoylation.

A mechanistic pathway by which EV-A71 co-opts MATR3 through condensate formation and palmitoylation to stabilize its genomic RNA and promote viral replication is delineated, and a comprehensive profiling dataset of host proteins associated with EV-A71 RNA is provided.

Xiaoyan Zuo, Yong-Jun Chen, Xia Xiao et al. · Proceedings of the National... · 0 citations

Open access Jul 2026

A functional genomics-pharmacotranscriptomics framework identifies host-directed anti-influenza agents

An integrative host-directed drug discovery framework combining functional genomics and pharmacotranscriptomics is developed, providing a systematic and scalable strategy for discovering antivirals that are less susceptible to resistance and potentially applicable to other rapidly evolving pathogens.

Jianfa Qiu, Xuecong Xing, Jing-Feng Wang et al. · iScience · 0 citations