Author

Jianxin Ye

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Open access Sep 2026

Development and external validation of an interpretable machine learning model for early prediction of in-hospital mortality in neurocritical care

Background Early risk assessment is a routine part of neurocritical care, yet mortality prediction remains difficult because neurological injury often coexists with respiratory, circulatory, renal, and inflammatory dysfunction. This study aimed to develop and externally validate an interpretable machine learning (ML) m...

Xiao Cheng, Jian-Xin Ye, H. Wei · Frontiers in Neurology · 0 citations

Open access Jul 2026

NRG1β-overexpressing mesenchymal stem cell-derived exosomes alleviate oxygen-glucose deprivation-mediated neuronal injury via the miR-296-3p/MAOA axis

It is demonstrated that exosomes derived from NRG1β-overexpressing mesenchymal stem cells (MSCs) exert neuroprotective effects against ischemic injury by upregulating miR-296-3p, which targets MAOA, leading to a reduction in apoptosis, oxidative stress, and inflammation.

Kui-Hua Wang, Haizhen Xu, Xiaohui Ji et al. · Frontiers in Cellular Neuros... · 0 citations