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Review Open access Aug 2026

Inflammatory remodeling of the ovarian microenvironment in premature ovarian insufficiency: mechanisms and therapeutic opportunities

Premature ovarian insufficiency (POI) is increasingly recognized as a disorder shaped not only by follicle-intrinsic defects but also by disruption of the ovarian tissue microenvironment. This Mini Review reframes POI as a process of inflammatory ovarian remodeling, in which immune activation, macrophage polarization,...

Jiao Fu, Qiaoling Wang, Xin-Yu Long et al. · 0 citations

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