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Review Open access Sep 2026

Chronic Inflammation, Fibrotic Remodeling, and Regenerative Failure in Duchenne Muscular Dystrophy: Mechanisms and Therapeutic Opportunities

This review integrates mechanistic and translational evidence linking dystrophin deficiency, FAP-centered stromal remodeling, immune–stem cell crosstalk, and tissue-specific differences between skeletal and cardiac muscle to define stage-specific and niche-directed strategies that complement dystrophin restoration.

Jie Shi, Jiao Yang · 0 citations

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