Author

Jiaxuan Liu

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Open access Oct 2026

hsa_circ_0001377 promotes hepatic fibrosis by sponging let-7a-5p and targeting TGFBR1, Smad2, and Col1a2

Background: Hepatic fibrosis (HF) is primarily driven by the activation of hepatic stellate cells (HSCs) and is characterized by excessive extracellular matrix (ECM) accumulation. Circular RNAs (circRNAs) have recently gained increasing attention in HF research. Methods: RNA sequencing and bioinformatic analyses reveal...

Jia-Ming Zhou, Jia-Xuan Liu, Di Wu et al. · Frontiers in Pharmacology · 0 citations

Open access Jan 2026

Shared Genetic Architecture and Pleiotropic Loci Linking Endometriosis and Inflammatory Bowel Disease: An Integrative GWAS, Colocalization, and Mendelian Randomization Study

Evidence is provided for a shared, albeit modest, and genetic basis between EMS and IBD that is likely mediated through immune regulation, hormonal signaling, and tissue repair that is likely mediated through immune regulation, hormonal signaling, and tissue repair.

Xinyue Cui, Jian-Hong Wang, Jingjing Chen et al. · BioMed Research Internationa... · 0 citations