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Author

Jiayan Fan

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Review Sep 2026

Novel insights into Retinoblastoma: From Oncogenic Circuitry to Precision Diagnosis and Eye-Preserving Therapies.

Retinoblastoma (RB) represents the most common primary intraocular malignancy in childhood and stands as a paradigm for translating molecular oncology into precision clinical management. This review synthesizes the comprehensive evolution in the understanding and treatment of RB. First, we deconstruct the intricate onc...

Min Zhou, Jie-Ling Tang, Xu-Yang Wen et al. · 0 citations
Review Aug 2026

Lactate Signaling and Lactylation in Retina: From Physiological Warburg Effect to Pathological Metabolic Reprogramming.

This review synthesize current advances in lactate signaling and lactylation in the retina, and examines how their dysregulation contributes to neovascularization, inflammation, and neurodegeneration in disorders including diabetic retinopathy, age-related macular degeneration, autoimmune uveitis and glaucoma.

Xiang Gu, Ai Zhuang, Jiayan Fan et al. · 0 citations

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