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Jie Deng

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Open access Jul 2026

Pleiotropic roles of the MATE transporter CD20030 in Clostridioides difficile: linking multidrug resistance to oxidative stress defense and virulence regulation

The MATE transporter (CD20030) operates as a pleiotropic regulatory hub and metabolic sentinel in C. difficile, indicating the involvement of this transporter in intrinsic resistance and oxidative defense and presenting a “swimming-to-sliding transition” driven by metabolic stress, rather than active swimming motility.

Jie Deng, Fa-Hui Chen, Wen-Jing Wu et al. · 0 citations

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