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Open access Sep 2026

Tekt2 regulates hair cell development and function by maintaining normal kinocilium morphology in zebrafish

Background Sensory hair cells (HCs) rely on a highly polarized apical apparatus, composed of actin-rich stereocilia and a microtubule-based kinocilium, to detect mechanical stimuli. Although tektins are conserved microtubule-associated proteins enriched in cilia and flagella, their roles in sensory HC morphogenesis and...

Biao Li, Po Xue, Jie Sun et al. · 0 citations
Open access Aug 2026

Transcriptomic profiling of inner ear hair cell spontaneous regeneration reveals the key role of dlx5a

Sensory hair cells (HCs) are susceptible to damage, typically causing permanent hearing and balance deficits in mammals due to limited regeneration. Understanding spontaneous regeneration in non-mammalian models offers key insights for restoring sensory function. Here, we establish a zebrafish semicircular canal crista...

Jie Gong, Chao Yang, Gui-Yi Zhang et al. · 0 citations

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